Each row is one combination of substitutions in an "interesting substitution group" seen in a natural sequence.

Barnes 2/3, 3 & escape & LCR

Members: 335F, 337R, 339L, 339R, 340Q, 346I. Root-only baseline: 116 sequences (100.00%).

Trees & matching sequences for this group →

combination	n subs	seqs	freq	top pango (combination)	most common form	n form	top pango (most common form)	most common form (vs closest pango)

Barnes 2/3, 3 & LCR

Members: 335F, 337R, 339L, 339R, 340Q, 345S, 346I, 346K, 440R, 445L, 446N. Root-only baseline: 114 sequences (98.28%).

Trees & matching sequences for this group →

combination	n subs	seqs	freq	top pango (combination)	most common form	n form	top pango (most common form)	most common form (vs closest pango)
RW.1.1 + P445L	1	2	1.72%	RW.1.1 (2)	RW.1.1 + P445L	2	RW.1.1 (2)	RW.1.1 + P445L

Barnes & escape & LCR

Members: 335F, 335S, 339L, 339R, 371Y, 377Y, 462Q, 462T, 487D, 493E, 516Q. Root-only baseline: 116 sequences (100.00%).

Trees & matching sequences for this group →

combination	n subs	seqs	freq	top pango (combination)	most common form	n form	top pango (most common form)	most common form (vs closest pango)

Barnes & LCR

Members: 333K, 334T, 335F, 335S, 337R, 339L, 339R, 340Q, 345S, 346A, 346I, 346K, 346S, 356N, 369F, 370T, 371Y, 372P, 376S, 377Y, 384T, 385I, 385P, 406Q, 408G, 417T, 429Y, 430I, 430P, 434L, 436S, 439K, 440R, 441H, 445L, 446N, 452R, 452S, 453F, 456V, 462Q, 462T, 468L, 473F, 474K, 478I, 481E, 481R, 481T, 482R, 482S, 484R, 485A, 486L, 486S, 487D, 487T, 490Y, 493E, 494P, 499H, 499T, 500A, 500N, 503I, 516Q, 518I. Root-only baseline: 114 sequences (98.28%).

Trees & matching sequences for this group →

combination	n subs	seqs	freq	top pango (combination)	most common form	n form	top pango (most common form)	most common form (vs closest pango)
RW.1.1 + P445L	1	2	1.72%	RW.1.1 (2)	RW.1.1 + P445L	2	RW.1.1 (2)	RW.1.1 + P445L

Barnes & very LCR

Members: 335F, 339L, 339R, 340Q, 345S, 346K, 356N, 417T, 430P, 440R, 462Q, 473F, 478I, 481R, 482R, 482S, 484R, 487D, 487T, 493E, 500A. Root-only baseline: 116 sequences (100.00%).

Trees & matching sequences for this group →

combination	n subs	seqs	freq	top pango (combination)	most common form	n form	top pango (most common form)	most common form (vs closest pango)

ACE2 proximal & LCR

Members: 406Q, 408G, 417T, 436S, 439K, 440R, 441H, 445L, 446N, 452R, 452S, 453F, 456V, 473F, 474K, 478I, 481E, 481R, 481T, 482R, 482S, 484R, 485A, 486L, 486S, 487D, 487T, 490Y, 493E, 494P, 499H, 499T, 500A, 500N, 503I, 508H, 508F. Root-only baseline: 114 sequences (98.28%).

Trees & matching sequences for this group →

combination	n subs	seqs	freq	top pango (combination)	most common form	n form	top pango (most common form)	most common form (vs closest pango)
RW.1.1 + P445L	1	2	1.72%	RW.1.1 (2)	RW.1.1 + P445L	2	RW.1.1 (2)	RW.1.1 + P445L