← index PY.1_matched — Selecting groups of interesting substitutions

Threshold-defined substitution groups

Barnes 2/3, 3 & escape & LCR

7 substitution(s) match

Trees marked with these substitutions →

Sequences containing combinations of these substitutions →

Trees marked with sequences containing combinations of these substitutions →

• Barnes 2/3, 3 & escape & LCR : escape_minus_updown_effect ≥ 0.05, lcr ≥ 1, n_obs ≥ 2, poslabel_antigenic_region ∈ {RBD Barnes 2/3, RBD Barnes 3} ±1 residues

Barnes 2/3, 3 & LCR

12 substitution(s) match

Trees marked with these substitutions →

Sequences containing combinations of these substitutions →

Trees marked with sequences containing combinations of these substitutions →

• Barnes 2/3, 3 & LCR : lcr ≥ 1, n_obs ≥ 2, poslabel_antigenic_region ∈ {RBD Barnes 2/3, RBD Barnes 3} ±1 residues

Barnes & escape & LCR

13 substitution(s) match

Trees marked with these substitutions →

Sequences containing combinations of these substitutions →

Trees marked with sequences containing combinations of these substitutions →

• Barnes & escape & LCR : escape_minus_updown_effect ≥ 0.1, lcr ≥ 0.5, n_obs ≥ 1, poslabel_antigenic_region ∈ {RBD Barnes 1, RBD Barnes 1/2, RBD Barnes 2, RBD Barnes 2/3, RBD Barnes 2/4, RBD Barnes 3, RBD Barnes 4} ±2 residues

Barnes & LCR

73 substitution(s) match

Trees marked with these substitutions →

Sequences containing combinations of these substitutions →

Trees marked with sequences containing combinations of these substitutions →

• Barnes & LCR : lcr ≥ 0.5, poslabel_antigenic_region ∈ {RBD Barnes 1, RBD Barnes 1/2, RBD Barnes 2, RBD Barnes 2/3, RBD Barnes 2/4, RBD Barnes 3, RBD Barnes 4} ±2 residues

Barnes & very LCR

25 substitution(s) match

Trees marked with these substitutions →

Sequences containing combinations of these substitutions →

Trees marked with sequences containing combinations of these substitutions →

• Barnes & very LCR : lcr ≥ 2, poslabel_antigenic_region ∈ {RBD Barnes 1, RBD Barnes 1/2, RBD Barnes 2, RBD Barnes 2/3, RBD Barnes 2/4, RBD Barnes 3, RBD Barnes 4} ±2 residues

ACE2 proximal & LCR

43 substitution(s) match

Trees marked with these substitutions →

Sequences containing combinations of these substitutions →

Trees marked with sequences containing combinations of these substitutions →

• ACE2 proximal & LCR : lcr ≥ 0.5, poslabel_ace2_proximity ∈ {proximal} ±2 residues